Agilent 300SB-C18 Analytical HPLC Col 4.6 x 150 883995-902

The Agilent ZORBAX 300SB‑C18 column (part number 883995‑902) is a 4.6 × 150 mm analytical reversed‑phase HPLC column built on stainless‑steel hardware. It employs a 300SB‑C18 stationary phase with 300 Å pores and 5 µm fully porous particles and is intended for LC and LC‑MS separations. Manufacturer specifications list peptide, protein and monoclonal‑antibody applications, so it is primarily used for biopharma and large‑molecule reversed‑phase separations as well as routine small‑molecule analyses under acidic to near‑neutral conditions.

Key Features:

• Separation Mode: Reversed‑phase
• Chemistry/Phase: ZORBAX 300SB‑C18
• Particle Size: 5 µm (fully porous)
• Length: 150 mm
• Inner Diameter: 4.6 mm
• Pore Size: 300 Å
• pH Range: 1–8 (maximum temperature rated to 90 °C)

Advantages:

• Manufacturer‑listed for peptides, proteins and monoclonal antibodies — suited to biopharma intact/subunit analyses.
• 300 Å pore size plus 5 µm particles support efficient mass‑transport and retention of larger biomolecules.
• Wide pH tolerance (1–8) and 90 °C max operating temperature allow robust methods with acidic mobile phases.
• Stainless‑steel hardware and 400 bar pressure rating provide durability and compatibility with routine HPLC/LC–MS workflows.