Agilent 300SB-C8 Analytical HPLC Col 4.6 x 150 883995-906

The Agilent ZORBAX 300SB-C8 (part number 883995-906) is an analytical reversed-phase HPLC column intended for liquid chromatographic separations of peptides, proteins and monoclonal antibodies. It uses 300SB-C8 chemistry on fully porous packing with a 300 Å pore size to improve access for larger biomolecules, and is supplied as a 4.6 x 150 mm stainless‑steel column for LC and LC/MS workflows.

Key Features:

• Phase: ZORBAX 300SB-C8
• Dimensions: 4.6 mm ID x 150 mm length
• Particle size: 5 µm (fully porous)
• Pore size: 300 Å
• Separation mode: Reversed phase
• Pressure rating: 400 bar; Max temperature: 80 °C
• Recommended pH range: 1–8

Advantages:

• Designed and specified for biopharma analytes (peptides, proteins, mAbs), providing improved retention and peak shape for larger molecules.
• Large 300 Å pores and 5 µm fully porous particles enhance mass transfer for biomolecules compared with small‑pore phases.
• Stainless‑steel hardware with 400 bar rating and 80 °C max temperature supports robust, routine analytical and LC/MS methods.
• Wide pH range (1–8) and reversed‑phase C8 chemistry offer method flexibility for diverse mobile phases and sample types.