Agilent 300SB-C8 Analytical HPLC Column 4.6x250 880995-906

The Agilent ZORBAX 300SB-C8 Analytical HPLC Column (part number 880995-906) is a reversed‑phase C8 LC column in a 4.6 x 250 mm format designed for LC and LC–MS use with larger biomolecules. Manufacturer specifications show a 300 Å pore size and 5 µm fully porous particles, and list intended applications in biopharma workflows such as peptides, proteins and monoclonal antibodies. The column is rated to 400 bar, supports operation up to 80 °C and a mobile‑phase pH range of 1–8, making it compatible with low‑pH and temperature‑assisted separations.

Key Features:

• Phase / Chemistry: ZORBAX 300SB-C8 (C8 bonded phase)
• Dimensions: 4.6 mm ID × 250 mm length
• Particle size: 5 µm (fully porous)
• Pore size: 300 Å
• Separation mode: Reversed‑phase; technique: LC and LC–MS

Advantages:

• Designed for large biomolecules — 300 Å pores improve access and separation of peptides, proteins and antibodies.
• Robust across low‑pH mobile phases and up to 80 °C, enabling TFA/formic‑acid methods and temperature‑assisted recovery.
• Laboratory‑grade pressure rating (400 bar) and fully porous particles for reproducible, high‑capacity analytical separations.