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Agilent 300SB-CN Analytical HPLC Column 4.6x250 880995-905

Agilent Technologies -- Item TECPIM000150602
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The Agilent ZORBAX 300SB-CN (part number 880995-905) is an analytical HPLC column (4.6 x 250 mm) using the 300SB-CN bonded phase designed for reversed-phase separations. It features 300 Å pore silica and 5 µm particles and is intended for biopharmaceutical LC and LC/MS applications, including peptides, proteins and monoclonal antibodies. The StableBond 300Å chemistry and rated pH range provide robustness for low-pH mobile phases commonly used in peptide/protein analysis.

Key Features:

  • Phase: 300SB-CN (cyano bonded phase)
  • Dimensions: 4.6 mm ID × 250 mm length
  • Particle size: 5 µm (fully porous)
  • Pore size: 300 Å
  • Operating range: pH 1–8; maximum temperature ≈80 °C; pressure rating ~400 bar

Advantages:

  • Wide 300 Å pores permit efficient access and separation of large biomolecules such as peptides and proteins.
  • StableBond chemistry offers improved stability in low-pH mobile phases used for LC/MS and TFA-containing methods.
  • Compatibility with LC and LC/MS workflows for biopharma analyses (mAbs, peptides, proteins) supports method transferability.
  • Ability to operate at elevated temperatures (up to ~80 °C) can improve recovery and chromatographic efficiency for difficult proteins.

Product Details

Overview
Model
Product Type Consumables
Part Number 880995-905
Brand Agilent Technologies
Gross Dimensions (WxDxH cm)
Net Dimensions (WxDxH cm)
Gross Weight (kg)
Net Weight (kg)
Specifications
Separation Mode Reversed Phase
Particle Size 5 µm
Length 250 mm
Inner Diameter 4.6 mm
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