Agilent Bio MAb,NP5,4.6x250mm,PK 5190-2407
Agilent Technologies -- Item TECPIM000092755
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The Agilent Bio MAb NP5 (part 5190-2407) is an analytical HPLC column packed with 5 µm non‑porous PS/DVB particles grafted with a hydrophilic polymeric layer and a weak cation‑exchange (WCX) phase. It is produced for high‑resolution, charge‑based separations and characterization of monoclonal antibody charge variants (acidic and basic isoforms). Typical use cases include charge‑variant analysis, protein/mAb method development and routine biopharmaceutical quality testing.
Key Features:
- Separation Mode: Ion Exchange — Weak Cation Exchange (WCX).
- Chemistry: Non‑porous PS/DVB beads grafted with a hydrophilic polymeric layer (WCX functionalization).
- Particle Size: 5 µm.
- Length: 250 mm.
- Inner Diameter: 4.6 mm.
- Hardware/Format: PEEK (PK version; biocompatible analytical column).
Advantages:
- Designed specifically for high‑resolution charge‑variant separations of monoclonal antibodies, enabling clear separation of acidic and basic isoforms.
- Hydrophilic polymer grafting minimizes nonspecific binding of antibody proteins, improving recovery and reproducibility.
- Robust non‑porous particle support and broad chemical compatibility support high capacity, method flexibility and stability across common mAb ion‑exchange conditions (manufacturer‑specified performance).
Product Details
Overview
| Model | |
|---|---|
| Product Type | Consumables |
| Part Number | 5190-2407 |
| Brand | Agilent Technologies |
| Gross Dimensions (WxDxH cm) | |
| Net Dimensions (WxDxH cm) | |
| Gross Weight (kg) | |
| Net Weight (kg) |
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