Agilent CN Analytical HPLC Column 4.6 x 250 880952-705

The Agilent ZORBAX Original CN analytical HPLC column (part number 880952-705) is a 4.6 x 250 mm, 5 µm cyano-modified silica column designed for analytical liquid chromatography. Its CN (cyano) phase provides distinct selectivity for polar and moderately polar compounds and supports both normal-phase and reversed-phase separations. Typical use cases include pharmaceutical, environmental and food analysis where separation of polar analytes is required.

Key Features:

• Dimensions: 4.6 mm ID × 250 mm length
• Particle size: 5 µm (fully porous)
• Phase/Chemistry: ZORBAX Original CN (cyano-modified silica)
• Pore size: 70 Å
• Pressure rating: 400 bar (maximum)
• pH range: 2–7; maximum recommended temperature: 60 °C

Advantages:

• Provides unique selectivity for polar and moderately polar compounds due to the cyano-modified stationary phase.
• Supports both normal-phase and reversed-phase methods, increasing method flexibility for diverse analytes.
• Robust physical specs (5 µm fully porous particles, 70 Å pores, 400 bar rating and 60 °C max) suitable for routine analytical HPLC workloads.
• Endcapped stationary phase and ~7% carbon load (manufacturer data) help reduce silanol interactions and improve peak shape for many analytes.