Agilent Extend-C18, 3.0x150mm 3.5um 763954-302

The Agilent ZORBAX Extend-C18 (part number 763954-302) is a reversed‑phase HPLC column with a 3.0 mm inner diameter, 150 mm length and 3.5 µm particle size, built on 80 Å fully porous silica. It is engineered for robust separations at elevated pH (stable from pH 2 to 11.5) using the Extend‑C18 bonded phase to allow silica‑based operation under basic conditions. Typical uses include reversed‑phase analyses of small molecules and peptides in routine HPLC and LC/MS workflows where high‑pH mobile phases improve analyte stability or solubility.

Key Features:

• Phase: ZORBAX Extend‑C18 (Extend‑C18 bonded phase)
• Dimensions: 3.0 mm ID × 150 mm length
• Particle size: 3.5 µm (fully porous)
• Pore size: 80 Å
• pH range: 2–11.5
• USP designation: L1
• Pressure rating: 400 bar; Maximum temperature 60 °C (pH 2–8), 40 °C (pH 8–11.5)
• Carbon load: 12.5%; Endcapped: double

Advantages:

• High pH stability (to pH 11.5) enables reliable separations of basic analytes that degrade or ionize under neutral/acidic conditions.
• Double endcapping and 12.5% carbon load deliver improved peak shape and broad applicability across compound classes.
• 400 bar rating and conventional hardware make the column compatible with standard HPLC/LC‑MS systems for routine laboratory workflows.