Agilent Extend-C18 Analytical, 5um, 4.6x250mm 770450-902
The Agilent ZORBAX Extend-C18 770450-902 is a reversed-phase HPLC analytical column (4.6 x 250 mm, 5 µm) designed for routine and high-pH separations. It uses the Extend-C18 bonded phase to provide high pH stability (operational range pH 2–11.5) so silica-based separations of basic compounds, peptides and small proteins can be performed with improved peak shape and LC/MS sensitivity. Typical use cases include method development and analysis of basic or pH-sensitive analytes in biopharma and analytical laboratories.
Key Features:
- Phase: ZORBAX Extend-C18 (C18 bonded phase)
- Dimensions: 4.6 mm ID x 250 mm length
- Particle size: 5 µm (fully porous)
- Pore size: 80 Å
- Operational pH range: 2–11.5
- USP classification: L1
- Endcapping: double endcapped
Advantages:
- High pH stability enables reliable separations of basic compounds and extended column lifetime under alkaline conditions.
- Improved peak shape and resolution for peptides and small molecules, aiding quantitation and method robustness.
- Compatible with LC/MS workflows (enhanced sensitivity when using volatile high‑pH buffers such as ammonium hydroxide).
- Conventional stainless steel hardware and 5 µm particles provide proven, reproducible performance for routine HPLC methods.
Product Details
Overview
| Model | |
|---|---|
| Product Type | Consumables |
| Part Number | 770450-902 |
| Brand | Agilent Technologies |
| Gross Dimensions (WxDxH cm) | |
| Net Dimensions (WxDxH cm) | |
| Gross Weight (kg) | |
| Net Weight (kg) |
Specifications
| Separation Mode | Reversed Phase |
|---|---|
| Particle Size | 5 µm |
| Length | 250 mm |
| Inner Diameter | 4.6 mm |
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