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Agilent Extend-C18 Analytical, 5um, 4.6x250mm 770450-902

Agilent Technologies -- Item TECPIM000150484
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The Agilent ZORBAX Extend-C18 770450-902 is a reversed-phase HPLC analytical column (4.6 x 250 mm, 5 µm) designed for routine and high-pH separations. It uses the Extend-C18 bonded phase to provide high pH stability (operational range pH 2–11.5) so silica-based separations of basic compounds, peptides and small proteins can be performed with improved peak shape and LC/MS sensitivity. Typical use cases include method development and analysis of basic or pH-sensitive analytes in biopharma and analytical laboratories.

Key Features:

  • Phase: ZORBAX Extend-C18 (C18 bonded phase)
  • Dimensions: 4.6 mm ID x 250 mm length
  • Particle size: 5 µm (fully porous)
  • Pore size: 80 Å
  • Operational pH range: 2–11.5
  • USP classification: L1
  • Endcapping: double endcapped

Advantages:

  • High pH stability enables reliable separations of basic compounds and extended column lifetime under alkaline conditions.
  • Improved peak shape and resolution for peptides and small molecules, aiding quantitation and method robustness.
  • Compatible with LC/MS workflows (enhanced sensitivity when using volatile high‑pH buffers such as ammonium hydroxide).
  • Conventional stainless steel hardware and 5 µm particles provide proven, reproducible performance for routine HPLC methods.

Product Details

Overview
Model
Product Type Consumables
Part Number 770450-902
Brand Agilent Technologies
Gross Dimensions (WxDxH cm)
Net Dimensions (WxDxH cm)
Gross Weight (kg)
Net Weight (kg)
Specifications
Separation Mode Reversed Phase
Particle Size 5 µm
Length 250 mm
Inner Diameter 4.6 mm
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