Agilent Extend-C18, Guard, 5u, 4.6x12.5mm 4PK 820950-930

Agilent ZORBAX Extend‑C18 guard cartridges (part number 820950-930) are 4-pack replacement guard cartridges (4.6 × 12.5 mm) packed with 5 µm fully porous Extend‑C18 sorbent for reversed‑phase HPLC. They are designed to protect analytical ZORBAX Extend‑C18 columns from particulates and strongly retained contaminants while maintaining chromatographic performance. The Extend‑C18 bonded phase with bidentate/double endcapping provides wide pH stability (pH 2–11.5), enabling high‑pH separations and compatibility with high‑pH mobile phases such as ammonium hydroxide to improve LC/MS sensitivity for peptides and small molecules.

Key Features:

• Phase: ZORBAX Extend‑C18 (C18)
• Separation mode: Reversed phase (HPLC)
• Particle size: 5 µm (fully porous)
• Inner diameter: 4.6 mm
• Length: 12.5 mm (guard cartridge)
• USP designation: L1
• pH range: 2–11.5; Pressure rating: 400 bar

Advantages:

• Enables robust high‑pH method development and stable separations up to pH 11.5
• Improves peak shape, retention and resolution for basic compounds and peptides
• Protects analytical columns and extends column lifetime by trapping particulates and strongly retained materials
• Supplied as a 4‑pack to provide ready replacements and reduce instrument downtime