Agilent Hi-Plex Ca USP L19, 250 x 4.0 mm PL1570-5810

The Agilent Hi‑Plex Ca USP L19 (PL1570-5810) is a ligand‑exchange/ion‑exclusion HPLC column designed and sold by Agilent for the analysis of carbohydrates, sugar alcohols and related small polar molecules. It meets the USP L19 designation and is intended for use on conventional HPLC systems with simple isocratic mobile phases (water or dilute acid), typically at elevated column temperatures to improve separation of mono‑ and disaccharides. Typical applications include routine carbohydrate profiling in food, beverage and biochemical samples and USP‑specified methods.

Key Features:

• Separation mode: Ion Exclusion / Ligand Exchange
• Chemistry (phase): Ca (calcium counter‑ion)
• Particle size: 8 µm
• USP designation: L19
• Length: 250 mm
• Inner diameter: 4.0 mm
• Maximum operating temperature: 90 °C

Advantages:

• Manufacturer‑recommended for accurate carbohydrate and sugar‑alcohol separations under USP L19 methods.
• Compatible with standard HPLC hardware and simple isocratic water or dilute‑acid mobile phases, avoiding specialized equipment.
• Rated to operate at elevated temperatures (up to ~90°C) to improve resolution of monosaccharides and anomer separations.
• Engineered media (monodisperse/8 µm) provides improved efficiency, lower operating pressures and extended column lifetime compared with conventional resins.